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Mean corpuscular hemoglobin concentration
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Mean corpuscular hemoglobin concentration : ウィキペディア英語版
Mean corpuscular hemoglobin concentration

The mean corpuscular hemoglobin concentration, a measure of the concentration of hemoglobin in a given volume of packed red blood cells. It is reported as part of a standard complete blood count.
It is calculated by dividing the hemoglobin by the hematocrit. Reference ranges for blood tests are 32 to 36 g/dL, or between 19.9 〔Converted with conversion factor from (). 1 g/dL = 0.6206 mmol/L〕 and 22.3〔 mmol/L. It is thus a mass or molar concentration.
Still, many instances〔(Blood Test Results - Normal Ranges ) Bloodbook.Com. Retrieved on Jan 7, 2009〕〔(MedicineNet > Definition of MCHC ) Last Editorial Review: 7/21/1999〕 measure MCHC in percentage (%), as if it were a mass fraction (mHb / mRBC). Numerically, however, the MCHC in g/dL and the mass fraction of hemoglobin in red blood cells in % are identical, assuming a RBC density of 1g/mL and negligible hemoglobin in plasma.
==Interpretation==
MCHC is diminished ("hypochromic") in microcytic anemias, and normal ("normochromic") in macrocytic anemias (due to larger cell size, though the hemoglobin amount or MCH is high, the concentration remains normal). MCHC is elevated ("hyperchromic") in hereditary spherocytosis, sickle cell disease and homozygous hemoglobin C disease.
This count is used to give a rough guide to what shade of red erythrocytes will be (i.e., the paler the color the lower the MCHC will be than the standard).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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